When we Consider about Ecology of Retroviruses have peculiar ecology. Retroviruses genomes can become integrated into the host cell chromosome. Once integrated, the viral genome (pro virus) may be transcribed or it may stay dormant and unsubscribed. If dormant, the retrovirus can exist undetected for a long time
Retroviruses have serious implications for HIV infections. HIV pro virus can integrate into the chromosome of a host white blood cell (lymphocyte) and remain undetected for years. Only when that lymphocyte is stimulated by some physiological signal will transcription of the pro virus be activated. Suddenly then, virus particles can burst from the cell and infect other nearby cells. This dormant state, termed viral latency, means that it is difficult, indeed virtually impossible, to eradicate an HIV infection from the body. Retroviruses can be many cells that harbor silent pro viruses; each is indistinguishable from a normal uninfected cells.
Retroviruses have serious implications for HIV infections. HIV pro virus can integrate into the chromosome of a host white blood cell (lymphocyte) and remain undetected for years. Only when that lymphocyte is stimulated by some physiological signal will transcription of the pro virus be activated. Suddenly then, virus particles can burst from the cell and infect other nearby cells. This dormant state, termed viral latency, means that it is difficult, indeed virtually impossible, to eradicate an HIV infection from the body. Retroviruses can be many cells that harbor silent pro viruses; each is indistinguishable from a normal uninfected cells.
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